
4th Annual Symposium for Life Science Innovation and Development
Tuesday, September 9, 2025 • Philadelphia, PA
Register Now

Philly Builds Bio+ 4th Annual Symposium for Life Science Innovation and Development
Tuesday, September 9, 2025
8 AM - 3 PM
QUORUM, UNIVERSITY CITY SCIENCE CENTER
3675 Market Street. Suite 400
Philadelphia, PA 19104
Join us at the Symposium and discover the latest innovations and connect with industry leaders shaping our city's thriving life science sector. Learn from experts, build valuable relationships, and stay ahead of market trends. By attending, you'll be part of the community driving Philadelphia's life science growth.



Photo Gallery
Program Speakers

Nina Ahmad
Philadelphia City Council
Councilmember | At Large

J. Todd Abrams
Innovation Nest (iNest),
Temple University
Executive Director

Kevin Batche
IPS – Integrated Project Services; Vice President, Procurement & Logistics

Sarajane Blair
CIC and Innovation Campus,
Science Center
General Manager

Melina Blees
BioLabs Philadelphia
Site Director

Tracy Brala
University City Science Center, Senior Vice President, Strategy and Partnerships

Matthew Burkhardt
B+Labs
Director

Michael J. Cerminaro
Thrombolex
Co-Founder, President & CEO

Robert Christmas
Pennsylvania Biotechnology Center
Chief Operating Officer

H. Jeffrey DeVuono
Brandywine Realty Trust, Executive VP and Senior Managing Director - Life Science

Jonathan Epstein
The Robert G. Dunlop Professor; Dean, Perelman School of Medicine; Executive VP, University of Pennsylvania Health System

Jamie Gauthier
Philadelphia City Council
Councilmember
3rd District

Mason Gibbs
University of Delaware
Senior Project Manager

Rebecca L Grant
City of Philadelphia Department of Commerce, Senior Director, Life Sciences & Innovation

James C. Greenwood
DLA Piper, Senior Policy Advisor (Retired); Biotechnology Innovation Organization, Past President and CEO; U.S. House of Representatives, Member (1993 – 2005)

Eric Hacherl
National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL), Viral Vector Program Lead

Denita Henderson
Pennovation Center
Managing Director

Louis P. Kassa III
Pennsylvania Biotechnology Center, Hepatitis B Foundation and Blumberg Institute, President

Nancy J Kelley
Nancy J Kelley + Associates
Founder & CEO; Builds Bio+, Co-Founder & Steering Committee Member

Brian Kirk
Orchestra Life Sciences
Vice President, Construction

Anyssa Lucena
Genuine Climbing, Founder
Breast Cancer Survivor;
AMGA Apprentice Rock Guide

Bridget Mackolin
EisnerAmper
Corporate Tax Senior Manager

Colin G. Miller
The Bracken Group
CEO and Co-Founder

Luis Montaner
The Wistar Institute, Executive Vice President; HIV Cure and Viral Diseases Center, Director; iCure, Co-principal Investigator

Stephen G. Nappi
Temple University, Associate Vice President, Technology Commercialization and Business Development

Justin D. Northrup
ThirdLaw Molecular
Principal Scientist,
Head of R&D

Thomas J. Piombino
IPS – Integrated
Project Services, Managing Director,
Americas

Anjali Rajadhyaksha
Center for Substance Abuse Research (CSAR), Director; Lewis Katz School of Medicine of Temple University, Professor, Department of Neural Sciences

Christopher J. Roberts
National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL), Associate Institute Director; University of Delaware, Professor of Chemical & Biomolecular Engineering

Michelle Roemer Schoen
Princeton Innovation Center BioLabs, Senior Event & Operations Manager

Mitchel Simpler
JBB, Partner Emeritus
Builds Bio+, Co-Founder &
Steering Committee Member

Kathy Spencer-Pike
Nucleus RadioPharma
Chief Commercial Officer

Jamie Sweet
Pennovation Works
Associate Director,
Education & Entrepreneurship

Maria Tripplaar
Ballard Spahr
Of Counsel

Drew Weissman
iCure, Co-principal Investigator; 2023 Nobel Laureate; Perelman School of Medicine at the University of Pennsylvania, Roberts Family Professor in Vaccine Research

Nelson Way
Ensemble
Vice President, Leasing and Development
Agenda
8:00 AM - 8:30 AM
REGISTRATION, BREAKFAST, AND
INCUBATOR / EXHIBITOR INNOVATION HALL
8:30 AM - 8:45 AM
WELCOME
SpeakerS:
-
- Nancy J Kelley, JD/ MPP
President & CEO, Nancy J Kelley + Associates
Founding Member, Builds Bio+
- Nancy J Kelley, JD/ MPP
-
- Jamie Gauthier
Councilmember, 3rd District, Philadelphia City Council
- Jamie Gauthier
-
- Rebecca L. Grant, DVM
Senior Director, Life Sciences & Innovation,
Department of Commerce, City of Philadelphia
- Rebecca L. Grant, DVM
8:45 AM – 9:15 AM
OPENING KEYNOTE: LEADING IN LIFE SCIENCES: BUILDING MOMENTUM IN GREATER PHILADELPHIA
Speaker:
-
- Jonathan A. Epstein, MD
The Robert G. Dunlop Professor; Dean, Perelman School of Medicine
Executive Vice President, University of Pennsylvania Health System
- Jonathan A. Epstein, MD
9:15 AM – 10:00 AM
RADIOPHARMACEUTICALS EMERGING AS REVOLUTIONARY NEW CANCER THERAPY
SPEAKERS:
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- Colin G Miller, PhD, CEO, The Bracken Group
- David Mankoff, MD. Professor and Vice Chair for Research, Department of Radiology at the University of Pennsylvania; Associate Director for Education and Training, Abramson Cancer Center
- Kathy Spencer-Pike, Chief Commercial Officer, Nucleas Radiopharma
The past two decades have brought a sea change in the way many types of cancer are treated and promise a transformation of radiation oncology in the next few years. Researchers are developing a new class of drugs called radiopharmaceuticals, which deliver radiation therapy directly and specifically to cancer cells. Philadelphia is a Center of Excellence for the development and commercialization of these treatments.
The last several years have seen an explosion of research and clinical trials testing new radiopharmaceuticals. These studies have suggested that targeting radiation therapy at the cellular level has the potential to reduce the risk of both short- and long-term side effects of treatment while at the same time enabling even tiny deposits of cancer cells to be killed throughout the body.
Due to their radioactive nature, radiopharmaceuticals are subject to strict regulations and are typically administered by specialists like nuclear medicine physicians.
Radiopharmaceuticals are produced through various methods, including nuclear fission, neutron reactions and the cyclotron method and require special facilities for both production and commercialization.
10:00 AM – 10:30 AM
TEMPLE UNIVERSITY’S MOST PROMISING NEW VENTURES
SPEAKERS:
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- Stephen G. Nappi, Associate Vice President, Technology Commercialization and Business Development, Temple University
REPRESENTATIVE COMPANIES:
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- Michael J. Cerminaro, Co-Founder, President & CEO, Thrombolex
Thrombolex, Inc., is an early stage medical device manufacturer focused on the design and development of endovascular catheter-based therapies for the treatment of acute venous thromboembolic disorders. The Company has developed a pool of medtech based intellectual property ("IP") in partnership with Temple University Research Hospital. Thrombolex is in the process of commercializing this IP Portfolio and is focused on completing a 510(k) regulatory pathway with the FDA.
- Michael J. Cerminaro, Co-Founder, President & CEO, Thrombolex
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- Justin D. Northrup, Principal Scientist, Head of R&D, ThirdLaw Molecular
ThirdLaw Molecular Inc. has pioneered the development of a groundbreaking new platform for targeted drug discovery. The mission of the Company is to create a revolutionary category of molecules that transform how diseases are diagnosed and treated – more safely and effectively.
- Justin D. Northrup, Principal Scientist, Head of R&D, ThirdLaw Molecular
10:30 AM – 11:00 AM
NETWORKING BREAK AND INCUBATOR/EXHIBITOR INNOVATION HALL
11:00 AM – 11:45 AM
2025 WASHINGTON IN REVIEW AND THE “BIG BEAUTIFUL BILL”
Moderator:
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- James C. Greenwood, Former Senior Policy Advisor, DLA Piper (Retired), Past President and CEO of the Biotechnology Innovation Organization (2005 – 2022) and Member of the U.S. House of Representatives (1993 – 2005)
SPEAKERS:
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- Bridget Mackolin, Corporate Tax Senior Manager, EisnerAmper
- Maria C. Tripplaar, Of Counsel, Ballard Spahr
- Kevin Batche, Vice President, Procurement & Logistics, Senior Associate, IPS-Integrated Project Services
- Anjali Rajadhyaksha, PhD, Director, Center for Substance Abuse Research; Professor, Department of Neural Sciences, Lewis Katz School of Medicine at Temple University
Get ahead of what’s coming with expert commentary on federal life science funding, tax implications for the biopharma and life sciences ecosystem and the impact of inflation on life science capital projects, amongst other things.
This session will cover the most impactful provisions of the recently enacted One Big Beautiful Bill Act—a sweeping update to the U.S. tax code that builds on, extends and permanently alters many elements of the 2017 Tax Cuts and Jobs Act (TCJA), as well as other developments in Washington since January, 2025.
11:45 AM – 12:00 PM
KEYNOTE: THE PATIENT PERSPECTIVE
Speakers:
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- Anyssa Lucena, Founder, Genuine Climbing
Breast Cancer Survivor and AMGA Apprentice Rock Guide
- Anyssa Lucena, Founder, Genuine Climbing
"CLIMBING WAS THERE TO HELP ME FEEL STRONG AND CAPABLE AGAIN. EVERY TOUCH OF THE ROCK GAVE ME A GLIMMER OF HOPE THAT THINGS WERE GOING TO BE OK."
"THERE IS NO BETTER THERAPY OR TREATMENT FOR THE SOUL THAN SUNSHINE, COOL AIR, HIGH FREQUENCY COMPANY AND A ROPE. CLIMBING IS GOOD MEDICINE AND I'M WRITING PRESCRIPTIONS FOR EVERYONE"
Anyssa has been climbing and guiding for over 15 years and strongly believes that climbing is a means to deeper healing and self-knowledge. Anyssa was diagnosed with Breast Cancer in 2022 and was inspired to turn her challenging experience into something that can help other women. Her cancer experience is a gift that she shares with other women, to help them know it’s going to be ok and to show them that it’s ok to feel disconnected and confused and still find their true, genuine selves at the end.
Genuine Climbing is dedicated to uplifting women both physically and emotionally by offering free rock climbing experiences for those affected by cancer. Rock climbing helps heal women dealing with cancer because it combines physical exercise with mental empowerment. The physical activity helps build strength, endurance, and flexibility, which are essential for recovery. Mentally, the challenge of climbing fosters resilience and a sense of accomplishment, helping to shift focus away from the illness. Add in a supportive environment and the healing power of nature and you have the best and most fun treatment you will ever experience.
12:00 PM – 12:50 PM
NETWORKING LUNCH AND
INCUBATOR / EXHIBITOR INNOVATION HALL
12:50 PM – 1:00 PM
WELCOME TO THE AFTERNOON SESSIONS
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- Dr. Nina Ahmad, Councilmember At-Large, Philadelphia City Council
1:00 PM – 1:30 PM
PHILADELPHIA HUB FOR ADVANCED MANUFACTURING
Speakers:
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- Nelson Way, Vice President, Leasing and Development, Ensemble
- Sumit Verma, Co-Founder & Partner, Orchestra Life Sciences
- Thomas J. Piombino, Managing Director, Americas, IPS-Integrated Project Services
Governor Josh Shapiro and Department of Community and Economic Development Secretary Rick Siger recently visited the Philadelphia Navy Yard to highlight a $30 million investment through the PA SITES (Pennsylvania Strategic Investments to Enhance Sites) program. The funding supports the development of the Philadelphia Navy Yard Greenway District, helping to transform 54 acres into shovel-ready sites for advanced manufacturing, life sciences, and commercial use that will help grow Pennsylvania’s economy, foster innovation, and create jobs. The investment in Philadelphia is part of the Governor’s first round of PA SITES funding — a total of $64 million awarded to 11 strategic sites across the Commonwealth.
The $30 million grant awarded to Ensemble/Mosaic Navy Yard LLC will fund utility infrastructure, soil excavation, grading, and stormwater management to develop the Greenway District — accelerating a transformative redevelopment at one of Philadelphia’s most strategic business campuses. This work will prepare six lots for up to 700,000 square feet of advanced manufacturing and commercial space — part of a broader $6 billion redevelopment effort expected to generate 12,000 new jobs. https://navyyard.org/blog/navy-yard-awarded-30-million-from-pa-sites-program-to-drive-job-growth-and-economic-development/
1:30 PM – 2:15 PM
NIIMBL’S PROJECT BLACKHAWK: TRANSPORTABLE BIOMANUFACTURING FOR NATIONAL READINESS
SPEAKERS:
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- Eric Hacherl, PhD, Viral Vector Program Lead, NIIMBL
- Thomas J. Piombino, Managing Director, Americas, IPS-Integrated Project Services
- Mason Gibbs, PMP, Sr. Project Manager, Planning and Project Delivery, University of Delaware
Led by the University of Delaware through the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL), Project Blackhawk pioneers a modular, pod-based approach to plasmid DNA manufacturing. This initiative demonstrates the feasibility of constructing GMP-capable facilities that are mobile, rapidly deployable, and adaptable to minimal infrastructure environments. Designed to surge biomanufacturing capacity in response to public health emergencies, Project Blackhawk exemplifies NIIMBL’s mission to de-risk and accelerate innovation in biopharmaceutical manufacturing while strengthening the U.S. workforce and economy.
2:15 PM – 2:45 PM
PHILADELPHIA LEADS HIV CURE RESEARCH
SPEAKERS:
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- Luis J. Montaner, D.V.M., D.Phil
Co-principal Investigator, iCure
Institute EVP and Founding Director
HIV Cure and Viral Diseases Center, The Wistar Institute
- Luis J. Montaner, D.V.M., D.Phil
-
- Drew Weissman, MD, PhD
Co-principal Investigator, iCure
2023 Nobel Laureate
Roberts Family Professor in Vaccine Research at the Perelman School of Medicine at the University of Pennsylvania
- Drew Weissman, MD, PhD
The HIV Cure and Viral Disease Center strives to transform scientific discoveries into real-world solutions that improve global health by advancing innovative, cutting-edge research in viral diseases and immunology to uncover future therapeutic targets and cure HIV and other viral infections. The Center is housed in a new $24 million, 25,000 sq ft Wistar North Campus at University City.
In August, 2025, The Wistar Institute announced that the National Institutes of Health (NIH) granted a five-year, $17 million research award to launch iCure Consortium, a Philadelphia-based consortium of more than 95 leading HIV researchers co-led by Dr. Montaner and Dr. Weissman. The goal of the iCure Consortium is to advance strategies to cure HIV through tailored personalized medicine.
Other institutions participating in this study include Johns Hopkins Medicine and iCure co-principal investigator Robert Siliciano, M.D., Ph.D., the University of Pennsylvania, Philadelphia FIGHT, the Ragon Institute at Harvard University, George Washington University, Duke University, and Massachusetts Institute of Technology.
2:45 PM – 3:30 PM
RECEPTION AND INCUBATOR/ EXHIBIT INNOVATION HALL
New: Developer Tours
Monday, September 8 • 2:00pm – 4:00pm
Get a first-hand look at the spaces shaping Philadelphia’s life sciences future.
As an exclusive add-on to the symposium, we’re offering guided developer tours of key innovation sites.
The tours will run from 2:00pm to 4:00pm, and allow up to 20 registrants/tour. Waitlist available.
* Tour fees cover on-site staffing and coordination costs.The lab tour experiences are provided at no charge by our generous host venues.




In March, 2025 BioLabs announced the expansion and renaming of its Philadelphia location to BioLabs for Advanced Therapeutics. The 53,000-square-foot incubator opening this fall will feature nine conference rooms, premium event space for life science gatherings, and a variety of specialized support labs focusing on microbiology, microscopy, process development, and more. While continuing its commitment to high-potential life science startups of all types, the newly upgraded facility will go beyond traditional coworking lab spaces by also offering an advanced suite of specialized equipment and tailored educational events designed to accelerate innovation in the advanced therapeutics sector.

Brandywine Realty Trust’s Innovation Platform
Empowered by Education, Ignited by Industry



Schuylkill Yards and Brandywine Realty Trust’s flexible innovation platform provides an exceptional ecosystem for companies to scale in place. With various options like 3151 Market Street (pictured left), Cira Centre (pictured center and right) and B+labs incubator space, there is unmatched potential for innovation and growth -- all with one trusted real estate partner.
Just steps away from 30th Street Station, Schuylkill Yards connects Center City’s established business district with University City’s renowned academic core. This thriving hub for forward-thinking companies offers proximity to top talent, cutting-edge research, in a community where innovation thrives.
University City’s thriving ecosystem, anchored by acclaimed educational and medical institutions, not only attracts talented individuals but also serves as a fertile ground for life science and tech companies. The proximity to top-tier research facilities, access to a skilled workforce, and a supportive network of innovation and funding opportunities make University City an ideal location for the growth and success of life science ventures.


uCity Square is Philadelphia’s most established, dynamic, collaborative, mixed-use innovation district, including more than 4.0M square feet of labs, offices, academic and clinical facilities, along with more than 750 apartment units and amenities.
Our Knowledge Community, uCity Square, developed by Wexford Science & Technology and the University City Science Center over the last 20 years, is home to major academic medical institutions, including Penn Medicine, Drexel University, Children’s Hospital of Philadelphia, the Wistar Institute and Monell Chemical Senses Center, along with more than 200 tenants and more than 10,000 employees.
Through an active and engaged tenant base, intentional and regular programming, and welcoming public spaces, the uCity Square community is the place for collaborations, breakthroughs, and creating opportunity for our tenants and the broader Philadelphia life science and startup community.



"I've learned more about the key players in the Life Science ecosystem in the Philly Area and hope to connect with them for future business connections."
– PHILLY BUILDS BIO+ Symposium Attendee



2025 Sponsors
Philly Builds Bio+ is an initiative that recognizes the immense opportunity and potential within the life science industry and aims to foster collaboration, knowledge sharing, and partnerships




Launched in 2018, Builds Bio+ aims to connect all segments of the life science ecosystem in major regional clusters, through events, research, industry reports and educational programs.
A 501(c)(3) nonprofit membership-driven organization, Builds Bio+ is dedicated to bringing the life sciences innovation community together, serving as the go-to place to find information about and assistance with growing, building and locating life science companies in the major life science clusters it serves.
Initially, Builds Bio+ focused on the growth and development of the life science cluster in New York City, but its work now encompasses the Greater NY Metro area (which includes New York City and surrounding counties of New York, Connecticut, New Jersey, and Pennsylvania.) In 2022, Builds Bio+ held the first annual Symposium in Philadelphia.
"I will draw from this experience to continue to design and build the facilities that allow the talented researchers to achieve the next breakthroughs."
– PHILLY BUILDS BIO+ Symposium Attendee














































