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4th Annual Symposium for Life Science Innovation and Development


Tuesday, September 9, 2025 • Philadelphia, PA


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Philly Builds Bio+ 4th Annual Symposium for Life Science Innovation and Development


Tuesday, September 9, 2025
8 AM - 3 PM

QUORUM, UNIVERSITY CITY SCIENCE CENTER
3675 Market Street. Suite 400
Philadelphia, PA 19104


Join us at the Symposium and discover the latest innovations and connect with industry leaders shaping our city's thriving life science sector. Learn from experts, build valuable relationships, and stay ahead of market trends. By attending, you'll be part of the community driving Philadelphia's life science growth.


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Program Speakers

Kevin Batche - Philly Builds Bio steering committee
Nina Ahmad

Philadelphia City Council
Councilmember | At Large


Kevin Batche - Philly Builds Bio steering committee
J. Todd Abrams

Innovation Nest (iNest),
Temple University
Executive Director


Kevin Batche - Philly Builds Bio steering committee
Kevin Batche

IPS – Integrated Project Services; Vice President, Procurement & Logistics


Sarajane Blair - Philly Builds Bio steering committee
Sarajane Blair

CIC and Innovation Campus,
Science Center 
General Manager


Melina Blees - Philly Builds Bio steering committee
Melina Blees

BioLabs Philadelphia 
Site Director


Tracy Brala - Philly Builds Bio steering committee
Tracy Brala

University City Science Center, Senior Vice President, Strategy and Partnerships


Matthew Burkhardt - Philly Builds Bio steering committee
Matthew Burkhardt 

B+Labs
Director


Michael J. Cerminaro - Philly Builds Bio steering committee
Michael J. Cerminaro

Thrombolex
Co-Founder, President & CEO


Robert Christmas - Philly Builds Bio steering committee
Robert Christmas

Pennsylvania Biotechnology Center 
Chief Operating Officer


H. Jeffrey DeVuono - Philly Builds Bio steering committee
H. Jeffrey DeVuono

Brandywine Realty Trust, Executive VP and Senior Managing Director - Life Science


Jonathan Epstein - Philly Builds Bio steering committee
Jonathan Epstein

The Robert G. Dunlop Professor; Dean, Perelman School of Medicine; Executive VP, University of Pennsylvania Health System


Jamie Gauthier - Philly Builds Bio steering committee
Jamie Gauthier

Philadelphia City Council
Councilmember
3rd District


Gibbs, Mason - Philly Builds
Mason Gibbs

University of Delaware
Senior Project Manager


Rebecca Grant - Philly Builds
Rebecca L Grant

City of Philadelphia Department of Commerce, Senior Director, Life Sciences & Innovation


James C. Greenwood - Philly Builds
James C. Greenwood

DLA Piper, Senior Policy Advisor (Retired); Biotechnology Innovation Organization, Past President and CEO; U.S. House of Representatives, Member (1993 2005)


Eric Hacherl - Philly Builds Bio steering committee
Eric Hacherl

National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL), Viral Vector Program Lead


Denita Henderson - Philly Builds Bio
Denita Henderson

Pennovation Center
Managing Director


Lou Kassa - Philly Builds Bio
Louis P. Kassa III

Pennsylvania Biotechnology Center, Hepatitis B Foundation and Blumberg Institute, President


Nancy J Kelley - Philly Builds Bio steering committee
Nancy J Kelley

Nancy J Kelley + Associates
Founder & CEO; Builds Bio+, Co-Founder & Steering Committee Member


Brian Kirk - Philly Builds Bio steering committee
Brian Kirk

Orchestra Life Sciences
Vice President, Construction


Anyssa Lucena - Philly Builds Bio steering committee
Anyssa Lucena

Genuine Climbing, Founder
Breast Cancer Survivor;
AMGA Apprentice Rock Guide


Bridget Mackolin - Philly Builds Bio steering committee
Bridget Mackolin

EisnerAmper
Corporate Tax Senior Manager


Dr. Colin G. Miller, Ph.D- Philly Builds Bio steering committee
Colin G. Miller

The Bracken Group
CEO and Co-Founder


Luis Montaner - Philly Builds Bio steering committee
Luis Montaner

The Wistar Institute, Executive Vice President; HIV Cure and Viral Diseases Center, Director; iCure, Co-principal Investigator


Stephen G. Nappi - Philly Builds Bio
Stephen G. Nappi

Temple University, Associate Vice President, Technology Commercialization and Business Development


Justin D. Northrup - Philly Builds Bio
Justin D. Northrup

ThirdLaw Molecular
Principal Scientist,
Head of R&D


Tom Piombino - Philly Builds Bio
Thomas J. Piombino

IPS – Integrated
Project Services
, Managing Director,
Americas


Anjali Rajadhyaksha - Philly Builds Bio
Anjali Rajadhyaksha

Center for Substance Abuse Research (CSAR), Director; Lewis Katz School of Medicine of Temple University, Professor, Department of Neural Sciences


Christopher J Roberts - Philly Builds Bio
Christopher J. Roberts

National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL), Associate Institute Director; University of Delaware, Professor of Chemical & Biomolecular Engineering


Michelle Roemer Schoen - Philly Builds Bio
Michelle Roemer Schoen

Princeton Innovation Center BioLabs, Senior Event & Operations Manager


Mitch Simpler - Philly Builds Bio
Mitchel  Simpler

JBB, Partner Emeritus
Builds Bio+, Co-Founder &
Steering Committee Member


Kathy Spencer-Pike - Philly Builds Bio
Kathy Spencer-Pike

Nucleus RadioPharma
Chief Commercial Officer


Jamie Sweet - Philly Builds Bio
Jamie Sweet

Pennovation Works
Associate Director,
Education & Entrepreneurship


Maria Tripplaar - Philly Builds Bio
Maria Tripplaar

Ballard Spahr
Of Counsel


Drew Weissman - Philly Builds Bio
Drew Weissman

iCure, Co-principal Investigator; 2023 Nobel Laureate; Perelman School of Medicine at the University of Pennsylvania, Roberts Family Professor in Vaccine Research


Nelson Way - Philly Builds Bio steering committee
Nelson Way

Ensemble
Vice President, Leasing and Development


Agenda


8:00 AM - 8:30 AM

REGISTRATION, BREAKFAST, AND
INCUBATOR / EXHIBITOR INNOVATION HALL

8:30 AM - 8:45 AM

WELCOME
SpeakerS:
    • Nancy J Kelley, JD/ MPP
      President & CEO, Nancy J Kelley + Associates
      Founding Member, Builds Bio+
    • Jamie Gauthier
      Councilmember, 3rd District, Philadelphia City Council
    • Rebecca L. Grant, DVM
      Senior Director, Life Sciences & Innovation,
      Department of Commerce, City of Philadelphia

8:45 AM – 9:15 AM

OPENING KEYNOTE: LEADING IN LIFE SCIENCES: BUILDING MOMENTUM IN GREATER PHILADELPHIA
Speaker:
    • Jonathan A. Epstein, MD
      The Robert G. Dunlop Professor; Dean, Perelman School of Medicine
      Executive Vice President, University of Pennsylvania Health System

9:15 AM – 10:00 AM

RADIOPHARMACEUTICALS EMERGING AS REVOLUTIONARY NEW CANCER THERAPY
SPEAKERS:
    • Colin G Miller, PhD, CEO, The Bracken Group
    • David Mankoff, MD. Professor and Vice Chair for Research, Department of Radiology at the University of Pennsylvania; Associate Director for Education and Training, Abramson Cancer Center
    • Kathy Spencer-Pike, Chief Commercial Officer, Nucleas Radiopharma

The past two decades have brought a sea change in the way many types of cancer are treated and promise a transformation of radiation oncology in the next few years. Researchers are developing a new class of drugs called radiopharmaceuticals, which deliver radiation therapy directly and specifically to cancer cells. Philadelphia is a Center of Excellence for the development and commercialization of these treatments.

The last several years have seen an explosion of research and clinical trials testing new radiopharmaceuticals. These studies have suggested that targeting radiation therapy at the cellular level has the potential to reduce the risk of both short- and long-term side effects of treatment while at the same time enabling even tiny deposits of cancer cells to be killed throughout the body.

Due to their radioactive nature, radiopharmaceuticals are subject to strict regulations and are typically administered by specialists like nuclear medicine physicians.
Radiopharmaceuticals are produced through various methods, including nuclear fission, neutron reactions and the cyclotron method and require special facilities for both production and commercialization.

10:00 AM – 10:30 AM

TEMPLE UNIVERSITY’S MOST PROMISING NEW VENTURES
SPEAKERS:
    • Stephen G. Nappi, Associate Vice President, Technology Commercialization and Business Development, Temple University
REPRESENTATIVE COMPANIES:
    • Michael J. Cerminaro, Co-Founder, President & CEO, Thrombolex

      Thrombolex, Inc., is an early stage medical device manufacturer focused on the design and development of endovascular catheter-based therapies for the treatment of acute venous thromboembolic disorders. The Company has developed a pool of medtech based intellectual property ("IP") in partnership with Temple University Research Hospital. Thrombolex is in the process of commercializing this IP Portfolio and is focused on completing a 510(k) regulatory pathway with the FDA.

    • Justin D. Northrup, Principal Scientist, Head of R&D, ThirdLaw Molecular

      ThirdLaw Molecular Inc. has pioneered the development of a groundbreaking new platform for targeted drug discovery.  The mission of the Company is to create a revolutionary category of molecules that transform how diseases are diagnosed and treated – more safely and effectively.

10:30 AM – 11:00 AM

NETWORKING BREAK AND INCUBATOR/EXHIBITOR INNOVATION HALL

11:00 AM – 11:45 AM

2025 WASHINGTON IN REVIEW AND THE “BIG BEAUTIFUL BILL”
Moderator:
    • James C. Greenwood, Former Senior Policy Advisor, DLA Piper (Retired), Past President and CEO of the Biotechnology Innovation Organization (2005 – 2022) and Member of the U.S. House of Representatives (1993 2005)
SPEAKERS: 
    • Bridget Mackolin, Corporate Tax Senior Manager, EisnerAmper
    • Maria C. Tripplaar, Of Counsel, Ballard Spahr
    • Kevin Batche, Vice President, Procurement & Logistics, Senior Associate, IPS-Integrated Project Services
    • Anjali Rajadhyaksha, PhD, Director, Center for Substance Abuse Research; Professor, Department of Neural Sciences, Lewis Katz School of Medicine at Temple University

Get ahead of what’s coming with expert commentary on federal life science funding, tax implications for the biopharma and life sciences ecosystem and the impact of inflation on life science capital projects, amongst other things.

This session will cover the most impactful provisions of the recently enacted One Big Beautiful Bill Act—a sweeping update to the U.S. tax code that builds on, extends and permanently alters many elements of the 2017 Tax Cuts and Jobs Act (TCJA), as well as other developments in Washington since January, 2025.

11:45 AM – 12:00 PM

KEYNOTE: THE PATIENT PERSPECTIVE
Speakers:
    • Anyssa Lucena, Founder, Genuine Climbing
      Breast Cancer Survivor and AMGA Apprentice Rock Guide

"CLIMBING WAS THERE TO HELP ME FEEL STRONG AND CAPABLE AGAIN. EVERY TOUCH OF THE ROCK GAVE ME A GLIMMER OF HOPE THAT THINGS WERE GOING TO BE OK."

"THERE IS NO BETTER THERAPY OR TREATMENT FOR THE SOUL THAN SUNSHINE, COOL AIR, HIGH FREQUENCY COMPANY AND A ROPE. CLIMBING IS GOOD MEDICINE AND I'M WRITING PRESCRIPTIONS FOR EVERYONE"

Anyssa has been climbing and guiding for over 15 years and strongly believes that climbing is a means to deeper healing and self-knowledge.  Anyssa was diagnosed with Breast Cancer in 2022 and was inspired to turn her challenging experience into something that can help other women.  Her cancer experience is a gift that she shares with other women, to help them know it’s going to be ok and to show them that it’s ok to feel disconnected and confused and still find their true, genuine selves at the end.

Genuine Climbing is dedicated to uplifting women both physically and emotionally by offering free rock climbing experiences for those affected by cancer.  Rock climbing helps heal women dealing with cancer because it combines physical exercise with mental empowerment. The physical activity helps build strength, endurance, and flexibility, which are essential for recovery. Mentally, the challenge of climbing fosters resilience and a sense of accomplishment, helping to shift focus away from the illness. Add in a supportive environment and the healing power of nature and you have the best and most fun treatment you will ever experience.

12:00 PM – 12:50 PM

NETWORKING LUNCH AND
INCUBATOR / EXHIBITOR INNOVATION HALL

12:50 PM – 1:00 PM

WELCOME TO THE AFTERNOON SESSIONS
    • Dr. Nina Ahmad, Councilmember At-Large, Philadelphia City Council

1:00 PM – 1:30 PM

PHILADELPHIA HUB FOR ADVANCED MANUFACTURING
Speakers:
    • Nelson Way, Vice President, Leasing and Development, Ensemble
    • Sumit Verma, Co-Founder & Partner, Orchestra Life Sciences
    • Thomas J. Piombino, Managing Director, Americas, IPS-Integrated Project Services

Governor Josh Shapiro and Department of Community and Economic Development Secretary Rick Siger recently visited the Philadelphia Navy Yard to highlight a $30 million investment through the PA SITES (Pennsylvania Strategic Investments to Enhance Sites) program. The funding supports the development of the Philadelphia Navy Yard Greenway District, helping to transform 54 acres into shovel-ready sites for advanced manufacturing, life sciences, and commercial use that will help grow Pennsylvania’s economy, foster innovation, and create jobs. The investment in Philadelphia is part of the Governor’s first round of PA SITES funding — a total of $64 million awarded to 11 strategic sites across the Commonwealth.

The $30 million grant awarded to Ensemble/Mosaic Navy Yard LLC will fund utility infrastructure, soil excavation, grading, and stormwater management to develop the Greenway District — accelerating a transformative redevelopment at one of Philadelphia’s most strategic business campuses. This work will prepare six lots for up to 700,000 square feet of advanced manufacturing and commercial space — part of a broader $6 billion redevelopment effort expected to generate 12,000 new jobs.  https://navyyard.org/blog/navy-yard-awarded-30-million-from-pa-sites-program-to-drive-job-growth-and-economic-development/

1:30 PM – 2:15 PM

NIIMBL’S PROJECT BLACKHAWK: TRANSPORTABLE BIOMANUFACTURING FOR NATIONAL READINESS
SPEAKERS:
    • Eric Hacherl, PhD, Viral Vector Program Lead, NIIMBL
    • Thomas J. Piombino, Managing Director, Americas, IPS-Integrated Project Services
    • Mason Gibbs, PMP, Sr. Project Manager, Planning and Project Delivery, University of Delaware

Led by the University of Delaware through the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL), Project Blackhawk pioneers a modular, pod-based approach to plasmid DNA manufacturing. This initiative demonstrates the feasibility of constructing GMP-capable facilities that are mobile, rapidly deployable, and adaptable to minimal infrastructure environments. Designed to surge biomanufacturing capacity in response to public health emergencies, Project Blackhawk exemplifies NIIMBL’s mission to de-risk and accelerate innovation in biopharmaceutical manufacturing while strengthening the U.S. workforce and economy.

2:15 PM – 2:45 PM

PHILADELPHIA LEADS HIV CURE RESEARCH
SPEAKERS:
    • Luis J. Montaner, D.V.M., D.Phil
      Co-principal Investigator, iCure
      Institute EVP and Founding Director
      HIV Cure and Viral Diseases Center, The Wistar Institute
    • Drew Weissman, MD, PhD
      Co-principal Investigator, iCure
      2023 Nobel Laureate

      Roberts Family Professor in Vaccine Research at the Perelman School of Medicine at the University of Pennsylvania

The HIV Cure and Viral Disease Center strives to transform scientific discoveries into real-world solutions that improve global health by advancing innovative, cutting-edge research in viral diseases and immunology to uncover future therapeutic targets and cure HIV and other viral infections.  The Center is housed in a new $24 million, 25,000 sq ft Wistar North Campus at University City.

In August, 2025, The Wistar Institute announced that the National Institutes of Health (NIH) granted a five-year, $17 million research award to launch iCure Consortium, a Philadelphia-based consortium of more than 95 leading HIV researchers co-led by Dr. Montaner and Dr. Weissman.  The goal of the iCure Consortium is to advance strategies to cure HIV through tailored personalized medicine.

Other institutions participating in this study include Johns Hopkins Medicine and iCure co-principal investigator Robert Siliciano, M.D., Ph.D., the University of Pennsylvania, Philadelphia FIGHT, the Ragon Institute at Harvard University, George Washington University, Duke University, and Massachusetts Institute of Technology.

2:45 PM – 3:30 PM

RECEPTION AND INCUBATOR/ EXHIBIT INNOVATION HALL

New: Developer Tours

Monday, September 8 • 2:00pm – 4:00pm


Get a first-hand look at the spaces shaping Philadelphia’s life sciences future.
As an exclusive add-on to the symposium, we’re offering guided developer tours of key innovation sites.

The tours will run from 2:00pm to 4:00pm, and allow up to 20 registrants/tour. Waitlist available.

* Tour fees cover on-site staffing and coordination costs.The lab tour experiences are provided at no charge by our generous host venues.

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In March, 2025 BioLabs announced the expansion and renaming of its Philadelphia location to BioLabs for Advanced Therapeutics. The 53,000-square-foot incubator opening this fall will feature nine conference rooms, premium event space for life science gatherings, and a variety of specialized support labs focusing on microbiology, microscopy, process development, and more. While continuing its commitment to high-potential life science startups of all types, the newly upgraded facility will go beyond traditional coworking lab spaces by also offering an advanced suite of specialized equipment and tailored educational events designed to accelerate innovation in the advanced therapeutics sector.





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Brandywine Realty Trust’s Innovation Platform
Empowered by Education, Ignited by Industry


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Schuylkill Yards and Brandywine Realty Trust’s flexible innovation platform provides an exceptional ecosystem for companies to scale in place. With various options like 3151 Market Street (pictured left), Cira Centre (pictured center and right) and B+labs incubator space, there is unmatched potential for innovation and growth -- all with one trusted real estate partner.

Just steps away from 30th Street Station, Schuylkill Yards connects Center City’s established business district with University City’s renowned academic core. This thriving hub for forward-thinking companies offers proximity to top talent, cutting-edge research, in a community where innovation thrives.

University City’s thriving ecosystem, anchored by acclaimed educational and medical institutions, not only attracts talented individuals but also serves as a fertile ground for life science and tech companies. The proximity to top-tier research facilities, access to a skilled workforce, and a supportive network of innovation and funding opportunities make University City an ideal location for the growth and success of life science ventures.



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uCity Square is Philadelphia’s most established, dynamic, collaborative, mixed-use innovation district, including more than 4.0M square feet of labs, offices, academic and clinical facilities, along with more than 750 apartment units and amenities.

Our Knowledge Community, uCity Square, developed by Wexford Science & Technology and the University City Science Center over the last 20 years, is home to major academic medical institutions, including Penn Medicine, Drexel University, Children’s Hospital of Philadelphia, the Wistar Institute and Monell Chemical Senses Center, along with more than 200 tenants and more than 10,000 employees.

Through an active and engaged tenant base, intentional and regular programming, and welcoming public spaces, the uCity Square community is the place for collaborations, breakthroughs, and creating opportunity for our tenants and the broader Philadelphia life science and startup community.


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    "I've learned more about the key players in the Life Science ecosystem in the Philly Area and hope to connect with them for future business connections."


    – PHILLY BUILDS BIO+ Symposium Attendee


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    2025 Sponsors

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    Bronze Sponsor


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    Lanyard Sponsor


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    Exhibit Booth Sponsors

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    Incubators & Life Science Portfolio Companies


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    Philly Builds Bio+ is an initiative that recognizes the immense opportunity and potential within the life science industry and aims to foster collaboration, knowledge sharing, and partnerships


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    Launched in 2018, Builds Bio+ aims to connect all segments of the life science ecosystem in major regional clusters, through events, research, industry reports and educational programs.

    A 501(c)(3) nonprofit membership-driven organization, Builds Bio+ is dedicated to bringing the life sciences innovation community together, serving as the go-to place to find information about and assistance with growing, building and locating life science companies in the major life science clusters it serves.

    Initially, Builds Bio+ focused on the growth and development of the life science cluster in New York City, but its work now encompasses the Greater NY Metro area (which includes New York City and surrounding counties of New York, Connecticut, New Jersey, and Pennsylvania.) In 2022, Builds Bio+ held the first annual Symposium in Philadelphia.


    A Special Full-Day Conference for Life Science, Design, and Real Estate Professionals

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    Tuesday, September 12, 2023
    8 AM - 3 PM

    The Union League of Philadelphia
    140 S Broad St, Philadelphia



    View SpeakersView AgendaView Event VideosView Photo Gallery

    Philadelphia has a remarkable history of scientific research and pharmaceutical development that spans centuries.


    From its early days as a center of medical education and innovation to the present, the city has played a crucial role in advancing scientific knowledge. Renowned institutions such as the University of Pennsylvania and the Wistar Institute have been pioneers in groundbreaking research across various disciplines, including medicine, biology, and chemistry. Philadelphia's scientific legacy is further exemplified by breakthroughs like Dr. Jonas Salk's development of the polio vaccine at the University of Pittsburgh. This rich history positions Philadelphia as a prominent hub for scientific innovation.

    One of the key strengths of Philadelphia's life science ecosystem lies in its diversity. The region boasts a vibrant and varied community of academic institutions, research organizations, and pharmaceutical companies. Esteemed universities such as the University of Pennsylvania, Drexel University, and Temple University, along with renowned research institutions like The Wistar Institute and The Children's Hospital of Philadelphia, form the backbone of this dynamic ecosystem. The diverse range of expertise and resources available in Philadelphia attracts top-tier talent from around the world, fostering collaboration and pushing the boundaries of scientific exploration.

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    Tuesday, October 1, 2024
    8 AM - 3 PM

    Crystal Tea Room
    100 Penn Square East
    Wanamaker Building, 9th Floor 
    Philadelphia, PA 1910



    View SpeakersView AgendaView Event VideosView Photo Gallery

    Philadelphia has a remarkable history of scientific research and pharmaceutical development that spans centuries.


    From its early days as a center of medical education and innovation to the present, the city has played a crucial role in advancing scientific knowledge. Renowned institutions such as the University of Pennsylvania and the Wistar Institute have been pioneers in groundbreaking research across various disciplines, including medicine, biology, and chemistry. Philadelphia's scientific legacy is further exemplified by breakthroughs like Dr. Jonas Salk's development of the polio vaccine at the University of Pittsburgh. This rich history positions Philadelphia as a prominent hub for scientific innovation.

    One of the key strengths of Philadelphia's life science ecosystem lies in its diversity. The region boasts a vibrant and varied community of academic institutions, research organizations, and pharmaceutical companies. Esteemed universities such as the University of Pennsylvania, Drexel University, and Temple University, along with renowned research institutions like The Wistar Institute and The Children's Hospital of Philadelphia, form the backbone of this dynamic ecosystem. The diverse range of expertise and resources available in Philadelphia attracts top-tier talent from around the world, fostering collaboration and pushing the boundaries of scientific exploration.

    "I will draw from this experience to continue to design and build the facilities that allow the talented researchers to achieve the next breakthroughs."


    – PHILLY BUILDS BIO+ Symposium Attendee

    John Anderson Fry - Philly Builds Bio steering committee
    John Anderson Fry 

    Drexel University
    President


    Nancy Kelley - Philly Builds Bio founder
    Nancy J Kelley

    Builds Bio+
    Founding Member,
    Nancy J Kelley + Associates
    President & CEO

    Mitchel Simpler - Philly builds bio
    Mitchel W. Simpler

    Builds Bio+
    Founding Member
    JB&B
    Partner Emeritus


    More Speakers to Come...

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